\begin
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% UNIVERSITY OF ILLINOIS JOURNAL OF MEDICINE - ARTICLE TEMPLATE
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% Instructions for Authors and Copywriters:
% 1. Fill in all sections marked with [PLACEHOLDER]
% 2. Uncomment ONE article type from the Article Type section below
% 3. Add your content in the marked sections
% 4. Compile with pdflatex or your preferred LaTeX compiler
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\documentclass[preprint]{uijm}
% Available options:
% - preprint: Two-column layout (standard submission format)
% - review: Single column with line numbers and double spacing
% - no_author: Hides author names for anonymous review
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% ARTICLE METADATA
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% EDITABLE: Fill in these required fields with your article information
\articletitle{[Insert Article Title Here]}
\correspondingauthor{[Corresponding Author Name]}
\publicationdate{[Month Day, Year]}
\email{[corresponding.author@email.com]}
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% ARTICLE TYPE SELECTION
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% EDITABLE: Uncomment EXACTLY ONE of the following article types
% Only one type can be selected - the template will error if multiple are chosen
%\originalarticle % For original research articles
%\reviewarticle % For systematic reviews and literature reviews
\clinicaltranslationarticle % For clinical translation research
%\editorial % For editorial pieces
%\creativework % For creative scholarly works
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% TITLE CONFIGURATION
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% EDITABLE: Set the article title (appears in header and on title page)
\setarticletitle{[Insert Article Title Here]}
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% AUTHOR AND AFFILIATION INFORMATION
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% EDITABLE: Add all authors with their corresponding affiliation numbers
% Format: \author[affiliation-number]{Author Name}
% Add as many authors as needed
\author[1]{[First Author Full Name]}
\author[2]{[Second Author Full Name]}
\author[3]{[Third Author Full Name]}
% Add more authors as needed: \author[4]{Fourth Author}
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% AFFILIATION DETAILS
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% EDITABLE: Provide complete affiliation information for each author
% Format: \affil[number]{Department, Institution \\ \texttt{email@address.com}}
\affil[1]{[Department/Division, Institution Name, City, State/Country]\\
\texttt{[first.author@email.com]}}
\affil[2]{[Department/Division, Institution Name, City, State/Country]\\
\texttt{[second.author@email.com]}}
\affil[3]{[Department/Division, Institution Name, City, State/Country]\\
\texttt{[third.author@email.com]}}
% Add more affiliations as needed
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% DOCUMENT BEGINS
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\begin{document}
% First page setup
\thispagestyle{plain}
\onecolumn
\maketitle
% Horizontal rule separator
\begin{center}
\noindent\rule{.9\textwidth}{.4pt}
\end{center}
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% ABSTRACT
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% EDITABLE: Replace placeholder text with your structured abstract
% Medical journals typically require: Introduction, Methods, Results, Discussion
% Word limit: 300 words maximum
\begin{abstract}
\noindent\textbf{\large ABSTRACT}
\medskip
\noindent\textbf{Introduction:} [Provide a brief background and rationale for the study. State the primary objective or research question. Recommended length: 2-3 sentences.]
\medskip
\noindent\textbf{Methods:} [Describe the study design, setting, participants, interventions (if applicable), and primary outcome measures. Include key methodological details. Recommended length: 3-4 sentences.]
\medskip
\noindent\textbf{Results:} [Present the main findings with key statistics or outcomes. Include the most important quantitative results. Recommended length: 3-4 sentences.]
\medskip
\noindent\textbf{Discussion:} [Summarize the principal conclusions and their clinical or research implications. Mention limitations if space permits. Recommended length: 2-3 sentences.]
\end{abstract}
% Horizontal rule separator
\begin{center}
\noindent\rule{.9\textwidth}{.4pt}
\end{center}
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% KEYWORDS
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% EDITABLE: Provide 3-6 relevant keywords for indexing
% Use MeSH terms when applicable for medical topics
\noindent\textbf{Keywords:} [Keyword 1], [Keyword 2], [Keyword 3], [Keyword 4], [Keyword 5]
\clearpage
\twocolumn
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% MAIN ARTICLE CONTENT
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% INTRODUCTION
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% EDITABLE: Replace with your introduction text
% Typical structure: Background, knowledge gap, study objective
\section{Introduction}
[Provide background information and context for your research. Establish the current state of knowledge in the field and identify gaps or controversies. Previous research has established important foundations in this area~\cite{example2024}. Recent systematic reviews have highlighted key considerations~\cite{clinical2023}. Clearly state the purpose and objectives of your study. This section typically spans 2-4 paragraphs for a standard research article.]
[Add additional paragraphs as needed to fully introduce your research question and its significance. Methodological approaches have evolved significantly~\cite{methodology2022}, providing new opportunities for investigation.]
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% METHODS/METHODOLOGY
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% EDITABLE: Replace with your methods section
% Include: Study design, participants, procedures, measurements, statistical analysis
\section{Methods}
\subsection{Study Design and Setting}
[Describe the overall study design (e.g., randomized controlled trial, cohort study, case-control study) and the setting where the research was conducted.]
\subsection{Participants}
[Describe the study population, including inclusion and exclusion criteria, recruitment methods, and sample size calculations if applicable.]
\subsection{Procedures and Interventions}
[Detail the procedures followed and any interventions administered. Include sufficient detail to allow replication.]
\subsection{Outcome Measures}
[List and define primary and secondary outcome measures. Describe how they were assessed.]
\subsection{Statistical Analysis}
[Describe the statistical methods used to analyze the data. Include software packages and significance levels.]
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% RESULTS
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% EDITABLE: Replace with your results
% Present findings objectively without interpretation
\section{Results}
\subsection{Participant Characteristics}
[Present baseline characteristics of study participants, often in table format. Table~\ref{tab:demographics} shows the baseline characteristics of participants in both groups. No significant differences were observed between groups at baseline.]
\subsection{Primary Outcomes}
[Report the main findings related to your primary research question. Include relevant statistics, confidence intervals, and p-values. Table~\ref{tab:outcomes} presents secondary outcome measures. For comprehensive longitudinal data, see Table~\ref{tab:comprehensive}.]
\subsection{Secondary Outcomes}
[Present additional findings related to secondary outcomes or exploratory analyses. Reference the full-width Table~\ref{tab:comprehensive} for detailed timepoint comparisons.]
\subsection{Subgroup Analyses}
[If applicable, present results from pre-specified subgroup analyses.]
%------------------------------------------------------------------------------
% INNOVATION (Required for Clinical Translation Articles)
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% EDITABLE: Replace with your innovation description
% This section is REQUIRED for Clinical Translation Articles
\section{Innovation}
[Clearly articulate the novel aspects of your research. Explain how your work advances the field beyond the current state of knowledge. Describe the translational impact and potential clinical applications. This section should demonstrate the innovative nature of your research and its potential to influence clinical practice or future research directions.]
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% DISCUSSION
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% EDITABLE: Replace with your discussion
% Interpret results, compare with literature, discuss limitations and implications
\section{Discussion}
\subsection{Principal Findings}
[Summarize the main results and their interpretation in the context of your research question.]
\subsection{Comparison with Existing Literature}
[Compare your findings with previous research. Discuss agreements and discrepancies with other studies.]
\subsection{Strengths and Limitations}
[Honestly discuss the strengths and limitations of your study. Address potential sources of bias and generalizability.]
\subsection{Clinical and Research Implications}
[Discuss the practical implications of your findings for clinical practice and future research directions.]
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% CONCLUSION
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% EDITABLE: Replace with your conclusion
% Concise summary of key findings and their significance
\section{Conclusion}
[Provide a concise conclusion that summarizes the key findings and their implications. Avoid introducing new information. This section is typically 1-2 paragraphs and should reinforce the main message of your article.]
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% FIGURES AND TABLES
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\clearpage % Start on new page
\section{Figures and Tables}
%------------------------------------------------------------------------------
% TABLES
%------------------------------------------------------------------------------
% EDITABLE: Add your tables here
% Reference tables in text as Table~\ref{tab:label}
% Use booktabs package for professional-looking tables
\subsection*{Tables}
% Example 1: Single-column table (fits within one column)
\begin{table}[ht]
\centering
\small % Reduce font size slightly to fit in column
\caption{Baseline characteristics of study participants. Values are presented as mean (SD) or n (\%).}
\label{tab:demographics}
\begin{tabular}{@{}lcc@{}} % @{} removes extra side padding
\toprule
\textbf{Characteristic} & \textbf{Group A} & \textbf{Group B} \\
\midrule
Age, years & 45.2 (12.3) & 47.8 (11.9) \\
Female, n (\%) & 24 (60) & 28 (70) \\
BMI, kg/m\textsuperscript{2} & 26.4 (4.2) & 25.9 (3.8) \\
Comorbid., n (\%) & 15 (37.5) & 18 (45) \\
\bottomrule
\end{tabular}
\end{table}
% Example 2: Simple bordered table (if preferred style)
\begin{table}[ht]
\centering
\small
\caption{Secondary outcome measures by treatment group.}
\label{tab:outcomes}
\begin{tabular}{|l|c|c|}
\hline
\textbf{Outcome} & \textbf{Treatment} & \textbf{Control} \\
\hline
Outcome 1 & 23.4 (5.1) & 21.2 (4.8) \\
Outcome 2 & 18.9 (3.2) & 19.5 (3.4) \\
Outcome 3 & 45.2 (8.9) & 42.1 (7.6) \\
\hline
\end{tabular}
\end{table}
% Example 3: Full-width table (spans both columns for larger data)
\begin{table*}[htb]
\centering
\caption{Comprehensive results showing all measured variables across study timepoints. This table spans the full page width to accommodate more columns. Use this format for complex data that won't fit in a single column.}
\label{tab:comprehensive}
\begin{tabular}{@{}lcccccc@{}}
\toprule
\textbf{Variable} & \textbf{Baseline} & \textbf{Week 4} & \textbf{Week 8} & \textbf{Week 12} & \textbf{p-value} & \textbf{Effect Size} \\
\midrule
Primary outcome & 25.3 (4.2) & 28.1 (4.5) & 31.2 (5.1) & 34.8 (5.3) & <0.001 & 0.82 \\
Secondary A & 45.6 (8.3) & 47.2 (8.1) & 49.8 (7.9) & 52.3 (8.2) & 0.003 & 0.45 \\
Secondary B & 12.4 (2.1) & 13.1 (2.3) & 14.2 (2.4) & 15.6 (2.6) & <0.001 & 0.67 \\
Exploratory 1 & 78.2 (12.4) & 76.5 (11.8) & 75.1 (11.2) & 73.8 (10.9) & 0.045 & -0.32 \\
Exploratory 2 & 34.5 (6.7) & 35.8 (6.9) & 37.2 (7.1) & 38.9 (7.4) & 0.012 & 0.38 \\
\bottomrule
\end{tabular}
\end{table*}
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% FIGURES
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% EDITABLE: Add your figures here
% Reference figures in text as (Fig.~\ref{fig:label})
% For multiple panels: (Figs.~\ref{fig:1}a, b, \ref{fig:2}c)
\subsection{Figures}
% Example: Single column figure
\begin{figure}[ht]
\centering
% Replace 'example-image' with your actual figure file
\includegraphics[width=0.9\columnwidth]{example-image}
\caption{[Figure caption should be concise yet descriptive. Include sufficient detail for the figure to be understood independently. Define all abbreviations used in the figure.]}
\label{fig:example1}
\end{figure}
% Example: Full-width figure (spans both columns)
\begin{figure*}[htb]
\centering
% Replace 'example-image' with your actual figure file
\includegraphics[width=0.85\textwidth]{example-image}
\caption{[Caption for full-width figure. Use this format for larger, more complex figures that require additional space. Ensure all elements are clearly visible and labeled.]}
\label{fig:example2}
\end{figure*}
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% SUPPLEMENTARY SECTIONS
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\newpage
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% FUNDING INFORMATION
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% EDITABLE: List all funding sources
\section*{Funding}
[List all sources of funding for the research. Include grant numbers and funding agency names. If no funding was received, state: "This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors."]
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% ACKNOWLEDGEMENTS
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% EDITABLE: Acknowledge contributors not listed as authors
\section*{Acknowledgements}
[Acknowledge individuals who contributed to the research but do not meet authorship criteria. Examples: technical assistance, writing assistance, statistical analysis, or material support. Ensure all acknowledged individuals have given permission to be named.]
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% AUTHOR CONTRIBUTIONS
%------------------------------------------------------------------------------
% EDITABLE: Specify each author's contribution (CRediT taxonomy recommended)
\section*{Author Contributions}
[Specify contributions using CRediT roles when applicable: Conceptualization, Methodology, Software, Validation, Formal Analysis, Investigation, Resources, Data Curation, Writing - Original Draft, Writing - Review \& Editing, Visualization, Supervision, Project Administration, Funding Acquisition. Example: J.D. and S.M. conceived the study. J.D. performed experiments. S.M. analyzed data. All authors wrote and approved the manuscript.]
%------------------------------------------------------------------------------
% CONFLICT OF INTEREST
%------------------------------------------------------------------------------
% EDITABLE: Declare any conflicts of interest
\section*{Competing Interests}
[Declare any financial, personal, or professional relationships that could be perceived as influencing the work. Include consulting fees, stock ownership, employment, patents, grants, or other relationships. If no conflicts exist, state: ``The authors declare no competing interests.'']
%------------------------------------------------------------------------------
% DATA AVAILABILITY
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% EDITABLE: Describe data availability if needed
\section*{Data Availability}
[Describe where and how the data supporting this study can be accessed. Examples: ``Data are available from the corresponding author upon reasonable request.'' OR ``All data are included in the manuscript and supplementary files.'' OR ``Data are available at [repository name and DOI].'' If data cannot be shared, explain why.]
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% REFERENCES
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% EDITABLE: Add your bibliography
% OPTION 1: Manual references (shown below)
% OPTION 2: Use BibTeX (uncomment bibliography commands and comment out thebibliography)
\newpage % Start references on new page for cleaner layout
\section*{References}
% Manual bibliography format
\begin{thebibliography}{99}
\bibitem{example2024}
Smith J, Doe J.
Example research article title.
\textit{Journal of Medical Research}. 2024;15(3):123--145.
doi:10.1234/jmr.2024.001
\bibitem{clinical2023}
Johnson M, Williams S, Brown D.
Clinical translation in modern medicine: A systematic review.
\textit{Clinical Research Journal}. 2023;42(8):567--589.
doi:10.1234/crj.2023.042
\bibitem{methodology2022}
Anderson E, Martinez C.
Advanced methodological approaches in clinical studies.
\textit{Methodology in Medicine}. 2022;28(12):1045--1067.
doi:10.1234/mim.2022.028
% Add more references here following the same format:
% \bibitem{uniquekey}
% Author(s).
% Article title.
% \textit{Journal Name}. Year;Volume(Issue):Pages.
% doi:XX.XXXX/xxxxx
\end{thebibliography}
% OPTION 2: If using BibTeX instead, uncomment these lines and remove the thebibliography above:
% \bibliographystyle{plain}
% \bibliography{references}
\end{document}
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% END OF TEMPLATE
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% Compilation Instructions:
% For manual references: pdflatex filename.tex (run twice for cross-references)
% For BibTeX: pdflatex → bibtex → pdflatex → pdflatex
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